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The 2022 Tandem Meetings | Reducing the toxicity of conditioning in HSC gene therapy

Luigi Naldini, MD, PhD, San Raffaele Telethon Institute for Gene Therapy, Milano, Italy, talks on the toxicity associated with chemotherapy or radiotherapy-based conditioning prior to hematopoietic stem cell (HSC) gene therapy in hematological diseases. Prof. Naldini underlines the importance of exploring strategies to reduce the short-term and long-term toxicity of these regimens, as well as to assess milder conditioning strategies. This interview took place at the Transplantation & Cellular Therapy (TCT) Meetings of ASTCT™ and CIBMTR® 2022 in Salt Lake City, Utah.