Rakesh Popat, BSc, MBBS, MRCP, FRCPath, PhD, University College London Hospitals, London, UK, describes the results of a real-world multicenter study which evaluated the safety and efficacy of daratumumab, bortezomib and dexamethasone (DVd) at first relapse in patients with multiple myeloma. Dr Popat highlights the CASTOR trial (NCT02136134), which led to the approval of this combination, and explains that the results of this real-world study reflect the findings of the CASTOR study, particularly in progression-free survival (PFS) and time to next treatment (TTNT). This interview took place at the 9th World Congress on Controversies in Multiple Myeloma (COMy) 2023, held in Paris, France.
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