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IMS 2026 | Cevostamab plus pomalidomide after BCMA-directed therapy in R/R multiple myeloma

Rakesh Popat, MBBS, MRCP, FRCPath, PhD, University College London Hospitals, London, UK, discusses the potential role of cevostamab plus pomalidomide following BCMA-directed therapy in patients with relapsed/refractory (R/R) multiple myeloma. He highlights the potential efficacy of the combination after BCMA antibody-drug conjugates or CAR T-cell therapy, while noting lower response rates following BCMA bispecific antibodies and the potential impact of immune dysfunction in this setting. This interview took place at the 23rd International Myeloma Society (IMS) Annual Meeting in Glasgow, UK.

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