In this video, Eunice Wang, MD, Roswell Park Comprehensive Cancer Center, Buffalo, NY, comments on the optimal treatment approach for patients with myelodysplastic syndromes (MDS) who develop secondary acute myeloid leukemia (sAML) following hypomethylating agent (HMA) therapy. Dr Wang notes that while venetoclax-azacitidine (ven-aza) can result in an overall response of around 50% in this patient population, intensive induction therapy followed by allogeneic transplantation may offer better outcomes for these patients. This interview took place at the 66th ASH Annual Meeting and Exposition, held in San Diego, CA.
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