Noemí Puig, MD, PhD, of the University Hospital Salamanca, Salamanca, Spain, discusses frailty in patient populations, and their under-representation in clinical trials as well as INSIGHT-MM (NCT02761187), a study evaluating the treatment and survival of multiple myeloma patients. This interview was recorded via an online conference call with The Video Journal of Hematological Oncology (VJHemOnc).