John Gribben, MD, DSc, FRCPath, FMed Sci, Barts Cancer Institute, London, UK, chairs the day 1 round up of the 1st International Workshop on CAR-T (iwCAR-T), held in Miami, FL, along with Noelle Frey, MD, University of Pennsylvania, Philadelphia, PA, and David Maloney, MD, PhD, Fred Hutchinson Cancer Research Center, Seattle, WA. Hear their thoughts on differences among CAR T-cell products, ethical issues in clinical trials, and product collection and manufacturing.