Matthew Jenner, MBBS, MRCP, FRCPath, PhD, of University Hospital Southampton NHS Foundation Trust, Southampton, UK, discusses data coming from the OPTIMISMM study (NCT01734928). This sub-analysis looked at patients with multiple myeloma treated with pomalidomide, bortezomib and dexamethasone after one prior line of therapy in patients pre-treated with bortezomib. This interview was recorded via an online conference call with The Video Journal of Hematological Oncology (VJHemOnc).