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ASH 2023 | VEN-AZA versus intensive chemotherapy as bridging therapy in patients with MDS

Andrius Žučenka, MD, Vilnius University Hospital Santaros Klinikos, Vilnius, Lithuania, presents findings from a retrospective real-world study comparing outcomes of bridging therapy for patients with myelodysplastic syndromes (MDS) treated with venetoclax and azacitidine (VEN-AZA) versus intensive chemotherapy. The study reveals comparable remission rates, bridging to transplant rates, and overall survival (OS) between the two groups. Notably, VEN-AZA demonstrates lower toxicity rates, especially in older and less fit patients. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

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Disclosures

Consultancy: Abbvie, Astellas, Pfizer, Novartis, Janssen
Honoraria: Abbvie, Astellas, Novartis, Janssen
Travel Expenses: Abbvie, Novartis, Janssen, Takeda