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EHA 2026 | ARCHIVE conditioning enables direct-to-transplant strategy in high-risk AML
Andrius Žučenka, MD, Vilnius University Hospital Santaros Klinikos, Vilnius, Lithuania discusses upfront allogeneic stem cell transplantation using the investigational ARCHIVE conditioning approach for patients with acute myeloid leukemia (AML). He explains how this strategy combines intensive leukemia control with transplant conditioning to move patients directly to transplant without conventional bridging therapy. Dr Žučenka reviews early efficacy results, toxicity considerations, and the potential of this paradigm to improve outcomes in high-risk and relapsed/refractory AML. This interview took place at the 31st Congress of the European Hematology Association (EHA) in Stockholm, Sweden.
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