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Charles Craddock, CBE, FRCP (UK), FRCPath, DPhil, University of Birmingham, Birmingham, UK, discusses the research underway through the UK IMPACT stem cell transplantation cooperative, including the PRO-DLI trial (NCT02856464), investigating whether prophylactic donor lymphocyte infusions (DLI) delivered as part of a planned schedule improves disease-free survival in patients with myeloid malignancies. This interview was recorded via an online conference call with The Video Journal of Hematological Oncology (VJHemOnc).