Maria-Victoria Mateos, MD, PhD, University of Salamanca, Salamanca, Spain, discusses the use of belantamab mafodotin in relapsed/refractory (R/R) multiple myeloma (MM) refractory to proteasome inhibitors, immunomodulatory agents, and refractory and/or intolerant to anti-CD38 monoclonal antibodies. This interview was recorded via an online conference call with The Video Journal of Hematological Oncology (VJHemOnc).