Uma Borate, MD, The Ohio State University, Columbus, OH, outlines the Phase I trial (NCT03874052) evaluating the use of the JAK2 inhibitor ruxolitinib with the BCL2 inhibitor venetoclax following the demonstration of ex vivo efficacy. This oral intervention was effective and well tolerated in patients with relapsed/refractory (R/R) acute myeloid leukemia (AML) who were heavily pretreated. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.
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