Bijal Shah, MD, Moffitt Cancer Center, Tampa, FL, provides an overview on the use of brexucabtagene autoleucel (brexu-cel) in patients treated with prior blinatumomab therapy, highlighting the poorer overall survival that was observed. Dr Shah also discusses the role of allogeneic stem cell transplantation (alloSCT) in this setting. This interview took place at the American Society of Clinical Oncology (ASCO) 2022 Annual Meeting in Chicago, IL.