Michael Dickinson, MBBS, DMedSc, FRACP, FRACPA, Peter MacCallum Cancer Centre, Melbourne, Australia, comments on the rationale and preliminary results of the COALITION study (NCT04914741) evaluating the safety and efficacy of glofitamab plus R-CHOP or glofitamab plus polatuzumab vedotin-R-CHP (pola-R-CHP) in patients with high-risk diffuse large B-cell lymphoma (DLBCL). Early data from the trial shows promising complete remission rates and good tolerability of the combination. This interview took place at the 17th International Conference on Malignant Lymphoma (ICML), held in Lugano, Switzerland.
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