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ASH 2020 | A Phase Ib trial of fixed-volume isatuximab infusion in newly-diagnosed multiple myeloma

Enrique M. Ocio, MD, PhD, Marqués de Valdecilla University Hospital, Santander, Spain, discusses efficacy and safety results from a Phase Ib study (NCT02513186) of novel drug combinations in multiple myeloma (MM). Bortezomib (V) and dexamethasone (d) with either cyclophosphamide (C) or lenalidomide (R) are widely used regimens in MM. Having shown potentiation when combined with bortezomib, isatuximab, a CD38 monoclonal antibody, was used in combination with VCd or VRd in 44 newly-diagnosed MM patients ineligible for transplant. This interview took place during the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, 2020.

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