ASH 2023 | Toxicity outcomes of anti-BCMA therapy in R/R MM: bispecific T-cell engagers vs belantamab mafodotin
Rakesh Popat, BSc, MBBS, MRCP, FRCPath, PhD, University College London Hospitals NHS Foundation Trust, London, UK, introduces a retrospective comparison of toxicity outcomes observed when treating patients with relapsed/refractory (R/R) multiple myeloma (MM) with anti-BCMA bispecific T-cell engagers (TCEs) versus the antibody-drug conjugate (ADC) belantamab mafodotin. Although treatment with bispecific antibodies is associated with a higher response rate, there is a greater risk of infections which must be treated with intravenous immunoglobulins. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.
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Disclosures
Consultancy: GSK
Honoraria: GSK, Janssen, BMS, AbbVie, Roche
Research Funding: GSK
Current Employment: University College London Hospitals NHS Foundation Trust
