Peihua Lu, MD, Lu Daopei Hospital, Langfang, China and Lu Daopei Institute of Hematology, Beijing, China, discusses future research in the field of chimeric antigen receptor T-cell (CAR-T) therapies, highlighting recent approvals in B-cell malignancies and myeloma, and commenting on the potential role of CAR-T therapies in T-cell and myeloid malignancies. Dr Lu also highlights the need to decrease toxicities, decrease the manufacturing costs and increase the duration of responses. This interview took place at the virtual European Hematology Association (EHA) Congress 2021.