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ASH 2022 | Evaluating the safety and efficacy of novel anti-CD7 universal CAR-T therapy in R/R T-ALL and T-LBL

Peihua Lu, MD, Beijing Lu Daopei Institute of Hematology, and Hebei Yanda Lu Daopei Hospital, Langfang, China, describes the results of a Phase I trial (NCT04620655) assessing the universal CAR-T cell (UCAR-T) RD13-01 in patients with heavily pre-treated, relapsed/refractory (R/R) T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LBL). The study reported a benefit with RD13-01 with respect to complete remission (CR), with high rates of measurable residual disease (MRD) negativity. This interview took place at the 64th ASH Annual Meeting and Exposition congress held in New Orleans, LA.

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