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ASH 2025 | An update on BET inhibition in myelofibrosis: data presented at ASH 2025

In this video, Claire Harrison, MD, FRCP, FRCPath, Guy’s and St Thomas’ NHS Foundation Trust, London, UK, provides a brief update on BET inhibition for the treatment of myelofibrosis (MF). Prof. Harrison highlights several studies presented at the ASH 2025 meeting, including PROMise (ISRCTN12451433) and MANIFEST (NCT02158858), that demonstrate the efficacy and tolerability of BET inhibitors in combination with JAK inhibitors. This interview took place at the 67th ASH Annual Meeting and Exposition, held in Orlando, FL.

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