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ASH 2025 | Genomic assessment of acquired mutations in patients with CLL treated with nemtabrutinib

Thomas Kipps, MD, PhD, UC San Diego Moores Cancer Center, La Jolla, CA, discusses the genomic assessment of acquired mutations in patients with chronic lymphocytic leukemia (CLL) treated with nemtabrutinib in the Phase II BELLWAVE-003 study (NCT04728893). Dr Kipps notes that analyzing patient samples before, during, and after treatment can provide valuable insights into the dynamics of subclonal evolution and the development of resistance. This interview took place at the 67th ASH Annual Meeting and Exposition, held in Orlando, FL.

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