In this special ‘One Big Question’ segment, Charles Craddock, CBE, FRCP(UK), FRCPath, DPhil, FMedSci, University of Birmingham, Birmingham, UK, shares his perspectives on the most important trial or development poised to transform frontline treatment in acute myeloid leukemia (AML) over the next three years, drawing focus on the increasing adoption of venetoclax-based regimens in patients going to transplant. This interview took place at the 7th International Workshop on Acute Leukemias (iwAL 2025), held in Washington, DC.
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