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ASH 2022 | Extended follow-up of the MASTER trial

Luciano Costa, MD, PhD, UAB School of Medicine, Birmingham, AL, discusses results from a long-term follow-up of the Phase II MASTER trial (NCT03224507), which evaluated the outcomes of measurable residual disease (MRD)-adapted treatment cessation in patients with newly diagnosed multiple myeloma (NDMM) treated with daratumumab, carfilzomib, lenalidomide and dexamethasone (Dara-KRd). Dr Costa also highlights the impact of chromosomal abnormalities on patient outcomes and the need to implement novel therapies for patients with ultra-high-risk disease. This interview took place at the 64th ASH Annual Meeting and Exposition congress in New Orleans, LA.

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Sanofi: Consultancy, Honoraria; Adaptive Biotechnologies: Consultancy, Honoraria; Bristol Myers Squibb: Consultancy, Honoraria, Research Funding; Genentech: Research Funding; AbbVie: Research Funding; Amgen: Consultancy, Honoraria, Research Funding; Janssen: Consultancy, Honoraria, Research Funding.