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ASH 2022 | Investigating LAVA-051 in R/R myeloma and CLL: pharmacodynamic and early clinical cata

Arnon Kater, MD, PhD, University of Amsterdam, Amsterdam, Netherlands, outlines early results from a Phase I/IIa study that assessed the efficacy of LAVA-051, a novel bispecific gamma-delta T-cell engager in patients with relapsed/refractory (R/R) multiple myeloma and chronic lymphocytic leukemia (CLL). Early clinical data suggest that Lava-051 is well-tolerated and efficacious. This interview took place at the 64th ASH Annual Meeting and Exposition congress in New Orleans, LA.

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Disclosures

Abbvie, Astra Zeneca, BMS, Janssen, Roche/Genentech: Research Funding; Janssen, LAVA: Patents & Royalties: Pending; Astra Zeneca, BMS, Roche/Gennetech, Janssen, Abbvie, LAVA: Membership on an entity’s Board of Directors or advisory committees; Abbvie, Astra Zeneca, Janssen: Other: Speakers fee; Amsterdam UMC, University of Amsterdam: Current Employment.