Nina Shah, MD, of the University of California, San Francisco, CA, discusses the advent of BCMA CAR-T therapy in multiple myeloma, highlighting data from the KarMMA trial (NCT03361748), updates with ciltacabtagene autoleucel (cilta-cel), and orvacabtagene autoleucel (orva-cel; NCT03430011). This interview was recorded via an online conference call with The Video Journal of Hematological Oncology (VJHemOnc).