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ASH 2023 | Real-world comparison of RVD vs D-RVD in newly diagnosed transplant-eligible multiple myeloma

Sagar Lonial, MD, Winship Cancer Institute of Emory University, Atlanta, GA, discusses the findings of a real-world comparison assessing lenalidomide, bortezomib, and dexamethasone (RVD) vs daratumumab-RVD (D-RVD) in patients with newly diagnosed transplant-eligible multiple myeloma (MM). This analysis included a wider diversity of patients than is seen in many trials, with results consistent across groups. Data suggest that D-RVD confers a progression-free survival (PFS) and overall survival (OS) benefit in patients. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

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Disclosures

Research Funding: Novartis, Janssen
Consultancy: AbbVie Inc, Amgen Inc, Bristol-Myers Squibb Company, Celgene Corporation, Genentech, a member of the Roche Group, GlaxoSmithKline, Janssen Biotech Inc, Novartis, Pfizer Inc, Takeda Pharmaceuticals USA Inc.
Advisory Committee: TG Therapeutics Inc:
Board of Directors with Stock: Bristol-Myers Squibb Company, Janssen Biotech Inc, Novartis, Takeda Pharmaceuticals USA Inc. Contracted Research: Janssen