SOHO 2023 | Novel strategies emerging for elderly patients with DLBCL and ongoing trials in this space
Pallawi Torka, MD, Memorial Sloan Kettering Cancer Center, New York City, NY, gives an overview of novel treatment strategies emerging for elderly patients with diffuse large B-cell lymphoma (DLBCL), highlighting the need for alternative therapies to the R-CHOP regimen. Dr Torka also comments on the importance of geriatric assessment-based studies to account for biological differences across fit, unfit, or frail elderly patients. Response-adapted studies may also help inform treatment decisions, with the use of predictive tools such as circulating tumor DNA (ctDNA) as part of interim analysis. Finally, the potential to explore chemotherapy-free regimens for the treatment of elderly patients is also mentioned. This interview took place at the Eleventh Annual Meeting of the Society of Hematologic Oncology (SOHO 2023) held in Houston, TX.
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Disclosures
Consultancy fees from Genentech, Genmab, Seagen, ADC therapeutics, TG therapeutics, Lilly USA.
