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SOHO 2023 | Approaching and managing relapsed high-risk myeloma

Marc Braunstein, MD, PhD, NYU Long Island School of Medicine, New York City, NY, shares some insights into the treatment and management of relapsed high-risk multiple myeloma (MM), emphasizing the importance of enrolling patients in clinical trials and offering triplet or quadruplet therapies as a standard of care (SOC). Dr Braunstein comments on the success of second-line multi-agent combinations in randomized clinical trials, and concludes by discussing the management of patients with triple-class refractory disease, who may benefit from clinical trials evaluating the early use of CAR-T therapy or bispecific antibodies. This interview took place at the Eleventh Annual Meeting of the Society of Hematologic Oncology (SOHO 2023) held in Houston, TX.

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Disclosures

AbbVie: Consultant (advisory board), Adaptive Biotechnologies: Consultant (advisory board)
ADC Therapeutics: Consultant (advisory board), American College of Physicians: MSKAP Question Writer, Bristol Myers Squibb: Consultant (advisory board), Janssen: Faculty bureau, Bristol Myers Squibb: Research funding, CTI Biopharma: Consultant (advisory board), Epizyme: Consultant (advisory board), Glaxosmithkline: Consultant (advisory board), Guidepoint: Consultant, Janssen: Consultant (advisory board), Janssen: Research funding, LAVA Therapeutics: Consultant (advisory board), Pfizer: Consultant (advisory board), Pfizer/ICON: Clinical independent reviewer, Sanofi: Consultant, Seagen: Consultant (advisory board)