Alok Srivastava, MD, FRACP, FRCPA, FRCP, Christian Medical College, Vellore, India, comments on how hemophilia care and therapeutic options for patients have changed over the years, drawing focus on the promise of agents such as emicizumab and fitusiran. This interview took place at the 30th Congress of the International Society on Thrombosis and Haemostasis (ISTH) 2022 held in London, UK.