Alok Srivastava, MD, FRACP, FRCPA, FRCP, Christian Medical College, Vellore, India, discusses his presentation at ISTH 2022, which focused on an analysis of two Phase III studies evaluating the safety and efficacy of fitusiran prophylaxis in patients with hemophilia A and B previously treated with bypassing agents. Results demonstrated that fitusiran prophylaxis reduced the quantity of bypassing agents and clotting factor concentrates needed, and also reduced treatment burden on patients. This interview took place at the 30th Congress of the International Society on Thrombosis and Haemostasis (ISTH) 2022 held in London, UK.