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EHA 2024 | Evaluating teclistamab step-up dosing & dose de-escalation in R/R myeloma in the real-world setting

Rahul Banerjee, MD, FACP, Fred Hutchinson Cancer Center, Seattle, WA, discusses the findings of a retrospective analysis that investigated teclistamab step-up dosing and treatment dose schedule de-escalation in the real-world setting. Dr Banerjee highlights that dosing patterns are evolving with the reduction of time toxicity in mind, as reflected by the fact that 20-30% of patients included in the analysis were de-escalated, some as soon as three months into treatment. This interview took place at the 29th Congress of the European Hematology Association (EHA) in Madrid, Spain.

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Disclosures

Consultancy: Adaptive Biotechnologies, Bristol-Myers Squibb/Celgene, Caribou Biosciences, Genentech, GlaxoSmithKline, Janssen, Karyopharm Therapeutics, Legend Biotech, Pfizer, Sanofi, SparkCures; Research Funding: Abbvie, Bristol-Myers Squibb/Celgene, Janssen, Novartis, Pack Health/Quest Diagnostics, Prothena, Sanofi.