Simon Rule, MD, Plymouth University, Plymouth, UK, speaks at the British Society for Haematology (BSH) 2019 Annual Meeting, held in Glasgow, UK. He discusses his research on the use of allogeneic stem cell transplantation as part of front-line therapy for mantle cell lymphoma (MCL), with results suggesting that this option should only be considered in a subgroup of patients at high risk of early progression following conventional therapy.