Farhad Ravandi, MD, University of Texas MD Anderson Cancer Center, Houston, TX, discusses early results of a Phase I dose-escalation study (NCT02520427) exploring the safety, tolerability, pharmacokinetics, pharmacodynamics and preliminary efficacy of AMG330, a bi-specific T-cell engager, in patients with relapsed and refractory (R/R) acute myeloid leukemia (AML). This interview was recorded via an online conference call with The Video Journal of Hematological Oncology (VJHemOnc).