ASH 2023 | The risk of thrombotic events in patients with MGUS: an analysis from the iStopMM trial
Sæmundur Rögnvaldsson, MD, PhD, University of Iceland, Reykjavik, Iceland, discusses a study investigating the risk of thrombotic events in patients who were screened for monoclonal gammopathy of undetermined significance (MGUS) in the iStopMM trial (NCT03327597). The study reveals a heightened susceptibility to venous thrombosis in this cohort, unrelated to increased M-protein concentration. Dr Rögnvaldsson proposes a hypothesis suggesting the existence of a pro-thrombotic protein interacting with M-protein, potentially triggering thrombosis. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.
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