Arnon Nagler, MD, Chaim Sheba Medical Center, Tel Aviv, Israel, briefly discusses the excitement around the COMy 2022 meeting, and highlights some of the topics being presented. Prof. Nagler also discusses how the myeloma treatment landscape is advancing with the introduction of novel immunotherapies. This interview took place at the 8th World Congress on Controversies in Multiple Myeloma (COMy) 2022, held in Paris, France.