Christopher Kanakry, MD, National Cancer Institute, talks on advances in approaches to prevent graft-versus-host disease (GvHD), highlighting that while several therapeutics have been found to reduce the risk and severity of acute GvHD – including abatacept and tacrolimus – few appear to have an impact on chronic GvHD. However, Dr Kanakry comments that ex vivo and in vivo T-cell depletion strategies may mitigate chronic GvHD. This interview took place at the 7th Congress on Controversies in Stem Cell Transplantation and Cellular Therapies (COSTEM) in Berlin, Germany.
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