Ola Landgren, MD, PhD, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, discusses recent advancements in multiple myeloma (MM) treatment, noting the approval of several immunotherapies in the US within the last two years. The effectiveness and durability of novel antibody treatments, regardless of transplant eligibility, suggest that these therapies may shift current treatment paradigms. Prof. Landgren also mentions the recent approval of isatuximab combined with standard-of-care bortezomib, lenalidomide, and dexamethasone (Isa-VRd) in transplant-ineligible, newly diagnosed patients and comments on whether Isa-VRd or daratumumab plus VRd (Dara-VRd) will be a better treatment strategy in this population. This interview took place at the 21st International Myeloma Society (IMS) Annual Meeting, held in Rio de Janeiro, Brazil.
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