Lucia Masarova, MD, The University of Texas MD Anderson Cancer Center, Houston, TX, presents a study evaluating the influence of splicing mutations (SPM) on outcomes in patients with myelofibrosis (MF) secondary to polycythemia vera (PV) or essential thrombocythemia (ET). Full molecular sequencing revealed distinct mutation patterns between patients with primary MF and post-ET/post-PV MF. Despite these differences, survival outcomes were comparable, with SRSF2 mutations exerting the most significant impact on survival. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.
These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.