Guy Pratt, MD, FRCP, FRCPath, of University of Birmingham, Birmingham, UK, reviews data coming from the OPTIMISMM study (NCT01734928). This sub-analysis looked at patients with multiple myeloma treated with pomalidomide, bortezomib and dexamethasone after one prior line of therapy in patients pre-treated with bortezomib. This interview was recorded via an online conference call with The Video Journal of Hematological Oncology (VJHemOnc).