Marco Ruella, MD, University of Pennsylvania, Philadelphia, PA, briefly discusses the challenges with developing efficacious CAR-T cell products for patients with chronic lymphocytic leukemia (CLL), and highlights the possibility of using combination approaches with Bruton’s tyrosine kinase (BTK) inhibitors as a therapeutic strategy in the future. This interview took place at the EBMT-EHA 5th European CAR T-cell Meeting held in Rotterdam, The Netherlands.
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