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SOHO 2024 | The evolution of BCL2 inhibition in CLL

John Seymour, MBBS, FRACP, PhD, Peter MacCallum Cancer Centre, Melbourne, Australia, discusses the history and evolution of BCL2 inhibition in chronic lymphocytic leukemia (CLL). He highlights the progression from early, less effective agents to potent BCL2 inhibitors that have become foundational in time-limited combination treatments for achieving high rates of measurable residual disease (MRD) negativity. This interview took place at the Twelfth Annual Meeting of the Society of Hematologic Oncology (SOHO 2024) congress in Houston, TX.

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