ASH 2023 | Efficacy of subsequent therapies for CLL patients treated in the MURANO trial
John Seymour, MBBS, FRACP, PhD, Peter MacCallum Cancer Centre, East Melbourne, Australia, discusses outcomes of subsequent therapies in patients with relapsed/refractory (R/R) chronic lymphocytic leukemia (CLL) treated with venetoclax plus rituximab compared to bendamustine plus rituximab in the MURANO trial (NCT02005471). There was a significant benefit in progression-free survival (PFS) for patients treated in the venetoclax arm, and follow-up therapy with both venetoclax-based regimens and BTK inhibitors was feasible. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.
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Disclosures
Honoraria: AstraZeneca, AbbVie, Beigene, BMS, Gilead, Hoffmann-La Roche, Janssen; Membership on an entity’s Board of Directors or advisory committees: AstraZeneca, AbbVie, Beigene, Genor Bio, BMS, Gilead, Hoffmann-La Roche, Janssen; Research Funding: AbbVie, F. Hoffmann-La Roche Ltd; Speakers Bureau: AbbVie, Beigene, Hoffmann-La Roche; Consultancy: TG Therapeutics, BMS, Hoffmann-La Roche.
