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EBMT 2024 | Barriers that remain in the treatment of pediatric ALL with CAR-T therapies

Christina Peters, MD, St. Anna Children’s Hospital, Vienna, Austria, addresses ongoing challenges in CAR-T therapy for pediatric acute lymphoblastic leukemia (ALL). CAR-T is approved only for relapsed/refractory (R/R) cases, where T-cells are frequently exhausted from prior treatments like chemotherapy or allogeneic stem cell transplantation (alloSCT). Furthermore, post-CAR-T relapses often necessitate subsequent alloSCT. This interview took place at the 50th Annual Meeting of the EBMT in Glasgow, Scotland.

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