ASH 2023 | Golcadomide, a novel CELMoD agent, with R-CHOP in patients with untreated a-BCL
Marc Hoffmann, MD, The University of Kansas, Kansas City, KS, discusses the results from the dose escalation and expansion phases of the ongoing CC-220-DLBCL-001 trial (NCT04884035), which aims to assess the safety and efficacy of golcadomide, a novel CELMoD agent, in combination with R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone) for the treatment of previously untreated aggressive B-cell lymphoma (a-BCL). This therapy approach has shown promising response rates and will now be investigated in a large randomized Phase III trial. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.
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Disclosures
Consultancy: Pharmacyclics LLC (an AbbVie Company)
Honoraria: Pharmacyclics LLC (an AbbVie Company)
