Michael Dickinson, MBBS, DMedSc, FRACP, FRACPA, Peter MacCallum Cancer Centre, Melbourne, Australia, discusses the key results of a Phase I study evaluating the use of YTB323, a novel autologous CAR-T therapy, for the treatment of diffuse large B-cell lymphoma (DLBCL). Dr Dickinson first discusses the manufacturing process used in the development of this product, and then highlights the promising results observed in patients. This interview took place at the European Hematology Association (EHA) Congress 2022 held in Vienna, Austria.