Nisha Joseph, MD, Winship Cancer Institute, Emory University, Atlanta, GA, discusses an analysis of real-world data comparing the responses and survival outcomes in standard- and high-risk newly diagnosed transplant-eligible patients with multiple myeloma (MM) who received an induction regimen of daratumumab, lenalidomide, bortezomib and dexamethasone (D-RVd) or RVd prior to transplantation. Adding daratumumab to the RVd regimen confers a benefit to depth of response, and early follow-up data suggest a positive impact on progression-free survival (PFS) and overall survival (OS) with D-RVd in both standard- and high-risk patients. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.
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