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ASH 2022 | Using RWD to evaluate the use of fedratinib as a potential bridge to HSCT in patients with MF

In this video, Aaron Gerds, MD, Cleveland Clinic, Cleveland, OH, describes the rationale and findings of a study that used real-world data (RWD) to assess the use of fedratinib as a bridging therapy for patients with myelofibrosis (MF) undergoing hematopoietic stem-cell transplantation (HSCT). Dr Gerds explains that this study supports the use of fedratinib as a potential bridge for HSCT, although larger-scale studies are required to confirm this. This interview took place at the 64th ASH Annual Meeting and Exposition congress in New Orleans, LA.

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Disclosures

Kratos Pharmaceuticals: Research Funding; Incyte Corporation: Research Funding; Imago BioSciences: Research Funding; Bristol Myers Squibb/Celgene: Consultancy, Membership on an entity’s Board of Directors or advisory committees; CTI BioPharma: Membership on an entity’s Board of Directors or advisory committees, Research Funding; Novartis: Consultancy, Membership on an entity’s Board of Directors or advisory committees; Accurate Pharmaceuticals: Research Funding; AbbVie: Consultancy, Membership on an entity’s Board of Directors or advisory committees; Sierra Oncology: Consultancy, Membership on an entity’s Board of Directors or advisory committees; Morphosys/Constellation: Consultancy, Membership on an entity’s Board of Directors or advisory committees, Research Funding; PharmaEssentia: Consultancy, Membership on an entity’s Board of Directors or advisory committees.