Maria Victoria Mateos, MD, PhD, University of Salamanca, Salamanca, Spain, discusses emerging therapies for triple-class refractory patients with multiple myeloma (MM). These include BCMA and GPRC5D-targeted agents like bispecifics, CAR-Ts, and belantamab mafodotin. For patients refractory to these treatments, ongoing research is focused on cereblon E3 ligase modulators (CELMoDs) and melflufen. This interview took place during the 2024 American Society of Clinical Oncology (ASCO) Meeting in Chicago, IL.
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