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ASH 2022 | New therapeutic approaches targeting XPO1-overexpression in TP53-mutated myeloid malignancies

In this video, Eric Padron, MD, Moffitt Cancer Center, Tampa, FL, discusses overexpression of XPO1 in TP53-mutated myeloid malignancies, which has been found to be a mechanism of resistance to eprenetapopt and azacitidine, opening up the possibility of new therapeutic approaches. This interview took place at the 64th ASH Annual Meeting and Exposition congress in New Orleans, LA.

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Disclosures

Incyte: Research Funding; Blueprint: Honoraria; Taiho: Honoraria; BMS: Research Funding; Kura: Research Funding; Stemline: Honoraria; Syntrix Pharmaceuticals: Research Funding.