Prithviraj Bose, MD, of The University of Texas MD Anderson Cancer Center, Houston, TX, discusses the rationale, study design and results from a Phase I/II study of ruxolitinib and decitabine in patients with post-myeloproliferative neoplasm acute myeloid leukemia (AML). This interview was recorded via an online conference call with The Video Journal of Hematological Oncology (VJHemOnc).