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ASH 2023 | A pro-inflammatory state & peak cytokines are associated with ide-cel toxicity & responses in MM
Doris Hansen, MD, Moffitt Cancer Center, Tampa, FL, shares details of a study investigating the association of pre-treatment bone marrow composition and serum cytokine levels with treatment-related toxicities and early responses in patients with triple-class exposed relapsed/refractory (R/R) multiple myeloma (MM) treated with idecabtagene vicleucel (ide-cel). Understanding the relationship between these factors may inform toxicity prevention and therapeutic optimization when treating patients with this CAR T-cell therapy. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.
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Disclosures
Consultancy: Bristol Myers Squibb, Karyopharm, Janssen, Pfizer; Membership on an entity’s Board of Directors or advisory committees: Bristol Myers Squibb, Pfizer; Research Funding: Bristol Myers Squibb, Karyopharm, International Myeloma Society Young Investigator Award, Pentecost Family Myeloma Research Center; Honoraria: OncLive, Survivorship
